Splendora 5% (Scalp Solution)

✔️ Uses of Splendora 5%

• Hair loss
• Alopecia Androgenetic
• Male pattern baldness

✔️ Side effects of Splendora 5%

• Excessive hair growth on the face
• Rash
• Edema (swelling)
• Skin irritation

✔️ How to use Splendora 5%

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use.

✔️ How Splendora 5% works

Splendora 5% is a potassium channel opener. Its vasodilation action expands the blood vessels. Therefore, when it is applied to the scalp, it helps to increase blood flow. This increased blood flow provides more nutrition and oxygen to the hair follicles, which prevents hair cell death and also enhances new hair growth. This is how it works to treat your alopecia (hair loss).

✔️ What if you forget to take Splendora 5%?

If you miss a dose of Splendora 5%, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

✔️ Quick Suggestions:

• Wash hands before and after application.
• It should only be applied directly to the scalp. If Splendora 5%  topical solution accidentally comes into contact with your eyes, nose, or mouth, rinse the area thoroughly with cold tap water.
• Do not wash your hair or use a hair dryer for 4 hours after applying Splendora 5% topical solution, as this may reduce the effectiveness of the medication.
• During the first 2 weeks of application, your hair loss may increase.
• This is normal and indicates that the Splendora 5%  topical solution is working.
• Take care not to let Splendora 5%  topical solution drip onto your face as this may cause unwanted facial hair growth.
• Prove of hair development may take 2 months or more of twice day-by-day applications.
• In case hair regrowth happens, utilization must have proceeded for proceeded hair development; re-grown hair may vanish within 3 to 4 months of halting and the thinning up top handle will proceed.
• Discontinue in the event that no enhancement after 1 year of utilization.

✔️ Pharmacology

Minoxidil acts on hair follicles by dilating blood vessels and inhibiting androgens, which increases the supply of oxygen, blood, and nutrients to the hair follicles, thereby stimulating hair growth. After application, an average of 1.4% of the total dose was absorbed by the normal intact scalp. The topical absorption of minoxidil increases with increasing dose, thereby increasing the frequency of administration and decreasing the barrier function of the stratum corneum. Serum concentrations of minoxidil and the systemic effects of topical minoxidil are controlled by the rate of drug absorption through the skin. After topical discontinuation, approximately 95% of the systemic absorption is eliminated within 4 days. Minoxidil and its metabolites are mainly excreted in the urine. 

✔️ Dosage of Splendora 5

• Minoxidil Topical Solution is for external use only and should be applied when the hair and scalp are clean and dry.
• Apply 1 ml (7 sprays) of Minoxidil topical solution twice daily at 12-hour intervals to the scalp, beginning at the center of the affected area and spreading the solution out to cover the entire affected area.
• The total daily application dose should not exceed 2ml.
• For the best results, Minoxidil topical solution should be allowed to remain on the scalp for about 4 hours before washing.
• The nighttime application should be done 2-4 hours before going to bed to allow the solution to dry out.
• Minoxidil topical solution should not be massaged into the scalp but applied lightly.
• A hair dryer should not be used to speed up the drying of the solution as it may decrease its effectiveness.
• Minoxidil topical solution should not be mixed with any hair oil.
• The drug should not be used more than two times a day, or be taken orally or applied to any other part of the body to avoid the risk of adverse effects and unwanted hair growth.
• More frequent use or longer application time has no effect on hair growth.
• In case of missing any daily applications of Minoxidil topical solution, the patient should continue with the next application.
   

✔️ Adult Dose

• Androgenetic Alopecia Male: Apply 1 mL of 2% or 5% solution to affected areas of scalp BID; no more than 2 ml in 24 hours Female: Apply 1 mL of 2% solution to affected areas of scalp BID It should be used twice daily for four months or more before evidence of hair growth can be expected.

✔️ Child Dose:

• <18 years old: Safety & efficacy not established

✔️ Administration of Splendora 5

• Hands should be washed immediately if Minoxidil topical solution is applied with the fingertips.
• Clinical experience with Minoxidil indicates that twice-daily applications for 4 months or more may be required before there is evidence of hair growth.
• To arrest hair fall, Minoxidil topical solution should be used for not less than 45 days.
• Depending upon the severity of hair loss or type and extent of baldness, a particular strength of Minoxidil topical solution may be selected.

✔️ Interaction

Due to the increased absorption of minoxidil, minoxidil topical solution should not be used with other topical medications known to disrupt the stratum corneum barrier (such as tretinoin or anthralin). Although there is no clinical evidence, it is theoretically possible that the absorption of minoxidil may potentiate orthostatic hypotension caused by peripheral vasodilators.

✔️ Contraindication

Minoxidil topical solution is contraindicated in patients with a history of hypersensitivity to Minoxidil or any of the other ingredients in the formulation such as propylene glycol or ethanol.

✔️ Pregnancy & Lactation

Minoxidil topical solution should not be used during pregnancy and breastfeeding.

✔️ Precautions & Warnings

• Splendora 5%  topical solution is more likely to cause scalp irritation. If scalp irritation persists or worsens, stop using minoxidil topical solution.
• Utilizing Minoxidil, the client ought to decide that the scalp is ordinary and sound.
• Patients with known cardiovascular infection or cardiac arrhythmia ought to contact a doctor sometime recently utilized Minoxidil.
• Minoxidil contains liquor, which can cause burning and bother the eye.
• Within the occasion of inadvertent contact with delicate surfaces (eye, rubbed skin, and mucous films) the zone ought to be washed with the expansive sum of cool tap water.

✔️ Storage Conditions

Store in a cool, dry place, protected from light. Keep out of the reach of children.